Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111168 | 0.76 | ATM (0.40) | ATMKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8424490 | 0.73 | ATM (0.48) | ATMNPC1RAB9AKDM4EGPR3 | |
| SCHEMBL3535166 | 0.73 | ATM (0.48) | ATMNPC1RAB9AKDM4EMAPT | |
| SCHEMBL4620642 | 0.73 | ATM (0.48) | ATMNPC1RAB9ABCL2KDM4E | |
| SCHEMBL4559941 | 0.73 | ATM (0.48) | ATMNPC1RAB9AKDM4EGPR3 | |
| SCHEMBL5259264 | 0.73 | ATM (0.48) | ATMNPC1RAB9AKDM4EGPR3 | |
| SCHEMBL6557052 | 0.72 | ATM (0.36) | ATMKDM4EGPR3 | |
| SCHEMBL9769252 | 0.70 | ATM (0.45) | ATMNPC1RAB9AKDM4EGPR3 | |
| SCHEMBL8423013 | 0.69 | ATM (0.44) | ATMNPC1RAB9ACYP1A2CYP2A6 | |
| SCHEMBL9769436 | 0.69 | ATM (0.44) | ATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | claimed |
| CN-113563272-A | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2021-10-29 | — | — | CN | claimed |
| CN-108033919-B | Method for synthesizing 2-phenyl quinazolinone compound by taking styrene compound as raw material | 温州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-108129402-B | Method for synthesizing 2-phenyl quinazolinone compound by taking tolane compound as raw material | 温州大学 | 2021-02-12 | — | — | CN | claimed |
| CN-116444444-A | Method for preparing 2-substituted quinazolinone compound | 盐城工业职业技术学院 | 2023-07-18 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-112125900-B | Synthetic method of isoquinolino-quinazolinone compound | 常州工程职业技术学院 | 2022-11-18 | — | — | CN | disclosed |
| CN-112958162-B | Palladium catalyst for catalyzing quinazolinone synthesis and olefination reaction | 江南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113563272-A | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-113563272-A | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2021-10-29 | — | — | CN | disclosed |
| EP-1696927-A2 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005065183-A2 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| CN-1476435-A | Fluorinated quinolones as antimitotic and antitumor agents | 北卡罗来纳查佩尔山大学 | 2004-02-18 | — | — | CN | disclosed |
| EP-1322615-A2 | FLUORINATED QUINOLONES AS ANTIMITOTIC AND ANTITUMOR AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6569870-B1 | Anticarcinogenic agents for breast and ovarian cancer | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2003-05-27 | — | — | US | disclosed |
| US-6562830-B1 | Compounds which prevent or induce the remission of existing precancerous or cancerous lesions or carcinomas would greatly reduce illness and death from cancer | CELL PATHWAYS, INC. | 2003-05-13 | — | — | US | disclosed |
| US-6562830-B1 | Compounds which prevent or induce the remission of existing precancerous or cancerous lesions or carcinomas would greatly reduce illness and death from cancer | CELL PATHWAYS, INC. | 2003-05-13 | — | — | US | disclosed |
| WO-2002026730-A2 | FLUORINATED QUINOLONES AS ANTIMITOTIC AND ANTITUMOR AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-04-04 | — | — | WO | disclosed |