Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419412 | 0.90 | ALDH1A1 (0.43) | NPSR1ADORA1MEN1KMT2AACLY | |
| SCHEMBL8424588 | 0.86 | TSHR (0.51) | CCR2NPSR1ADORA1MEN1POLB | |
| SCHEMBL8421622 | 0.84 | ALDH1A1 (0.40) | NPSR1ADORA1ACLYLMNATP53 | |
| SCHEMBL8421510 | 0.82 | SLC22A12 (0.39) | CCR2NPSR1MEN1POLBKMT2A | |
| SCHEMBL8421498 | 0.81 | ALDH1A1 (0.44) | NPSR1MEN1POLBKMT2AACLY | |
| SCHEMBL8519903 | 0.81 | MAPT (0.41) | ACLYLMNATP53MAPTSLC22A12 | |
| SCHEMBL8423226 | 0.80 | ALDH1A1 (0.48) | NPSR1MEN1POLBKMT2ALMNA | |
| SCHEMBL8420124 | 0.79 | ALDH1A1 (0.39) | NPSR1MEN1KMT2AACLYLMNA | |
| SCHEMBL8087346 | 0.79 | MAPK13 (0.48) | NPSR1ADORA1MEN1POLBKMT2A | |
| SCHEMBL8095193 | 0.79 | CNR1 (0.46) | NPSR1ADORA1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |