Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
| ▸ | CHUK | O15111 | 3/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423745 | 0.77 | SOD1 (0.47) | SOD1KDM4ECYP1A2 | |
| SCHEMBL8425349 | 0.77 | NQO1 (0.46) | ALDH1A1NQO1KDM4ELMNAMAPT | |
| SCHEMBL8421272 | 0.77 | MCL1 (0.46) | SOD1ALDH1A1HTR3AKDM4ELMNA | |
| SCHEMBL8421485 | 0.74 | SOD1 (0.51) | SOD1ALDH1A1KDM4E | |
| SCHEMBL14611339 | 0.72 | NPC1 (0.67) | ALDH1A1KDM4ELMNAMAPTTDP1 | |
| SCHEMBL28691104 | 0.71 | IDO1 (0.50) | ALDH1A1IKBKBCHUKNQO1KDM4E | |
| SCHEMBL8421424 | 0.71 | SOD1 (0.56) | SOD1ALDH1A1KDM4ELMNAKCNH2 | |
| SCHEMBL25861219 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1ADORA3MAOA | |
| SCHEMBL26433552 | 0.70 | KDM4E (0.62) | ALDH1A1KDM4ELMNAMAPTTDP1 | |
| SCHEMBL18454567 | 0.70 | GOT1 (0.66) | SOD1ALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440787-B1 | COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR INVESTIGACION (ES) | 1999-10-13 | — | — | EP | disclosed |
| US-5719282-A | PARASITICIDES; ANTICANCER AGENTS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1998-02-17 | — | — | US | disclosed |
| EP-0440787-A1 | NEW COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1991-08-14 | — | — | EP | disclosed |