Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306554 | 0.84 | BACE1 (0.62) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL13445421 | 0.81 | BACE1 (0.44) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL18733969 | 0.81 | ADORA2A (0.56) | ALOX5BACE1ALDH1A1HPGDMEN1 | |
| SCHEMBL338655 | 0.80 | ERN1 (0.46) | ALOX5BACE1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10388224 | 0.79 | BACE1 (0.42) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL19019376 | 0.78 | CNR1 (0.42) | ALOX5BACE1ESR2MEN1KMT2A | |
| SCHEMBL6307069 | 0.77 | BACE1 (0.41) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL1032857 | 0.77 | BACE1 (0.41) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL25384655 | 0.77 | PDCD1 (0.44) | ALOX5BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL31087300 | 0.77 | BACE1 (0.52) | ALOX5BACE1ALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10465115-B2 | Cinnamic acid derivatives | MERCK PATENT GMBH (DE) | 2019-11-05 | — | — | US | disclosed |
| US-5985853-A | β-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |
| CN-1181757-A | Novel 'beta'-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides | HOECHST SCHERING AGREVO SA (FR) | 1998-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10465115-B2 | Cinnamic acid derivatives | RCC1, LSS, C1S | ALOX5 234/4885BACE1 662/4885ALDH1A1 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.