SCHEMBL6307069

SCHEMBL6307069

Ic1ccc(-c2ccc(I)cc2-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.41
ALOX5 P09917 1/20 0.40
PTGS2 P35354 4/20 0.37
ESR2 Q92731 2/20 0.36
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
XBP1 P17861 1/20 0.36
PTBP1 P26599 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
GALK1 P51570 1/20 0.36
BLM P54132 1/20 0.36
SMAD3 P84022 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032857 1.00 BACE1 (0.41) BACE1ALOX5PTGS2ESR2MEN1
SCHEMBL13445421 0.95 BACE1 (0.44) BACE1ALOX5PTGS2ESR2ALDH1A1
SCHEMBL22815354 0.88 HPRT1 (0.44) ESR2MEN1NPC1LMNAMAPT
SCHEMBL24658103 0.88 HPRT1 (0.44) ESR2MEN1NPC1LMNAMAPT
SCHEMBL6307073 0.87 PDE4A (0.38) BACE1ALOX5ESR2LMNAMAPT
SCHEMBL24658105 0.87 PDE4A (0.38) BACE1ALOX5ESR2LMNAMAPT
SCHEMBL19658348 0.85 PTGS2 (0.46) BACE1PTGS2ALDH1A1HSD17B10HPGD
SCHEMBL30913227 0.85 PTGS2 (0.46) BACE1PTGS2ALDH1A1HSD17B10HPGD
SCHEMBL24656817 0.84 HDAC7 (0.44) ESR2MEN1NPC1LMNAMAPT
SCHEMBL24882501 0.83 PTGS2 (0.45) BACE1PTGS2MEN1APAF1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107963972-B Organic electroluminescent device 保土谷化学工业株式会社 2021-09-03 CN disclosed
EP-3220437-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-04-14 EP disclosed
EP-3244462-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2020-11-11 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
EP-2960958-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2018-10-31 EP disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
EP-3244462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3220437-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-09-20 EP disclosed
US-20160126464-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 US disclosed
US-20150380657-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2015-12-31 US disclosed
EP-2960958-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2015-12-30 EP disclosed
US-9048435-B2 Organic semiconducting materials and organic component NOVALED AG (DE) 2015-06-02 US disclosed
US-20120223296-A1 Organic Semiconducting Materials and Organic Component SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2012-09-06 US disclosed
US-6936679-B2 Charge-transporting polymer FUJI XEROX CO., LTD. (JP) 2005-08-30 US disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
US-20030207187-A1 Charge-transporting polymer FUJI XEROX CO., LTD. (JP) 2003-11-06 US disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 BACE1 3680/4885ALOX5 1877/4885PTGS2 3841/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 BACE1 3680/4885ALOX5 1877/4885PTGS2 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.