Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421813 | 0.96 | KAT6A (0.44) | KAT6AMALT1GAAKDM1AMAOA | |
| SCHEMBL8420103 | 0.90 | PTGS2 (0.45) | KAT6AMALT1KDM1AMAOAAURKA | |
| SCHEMBL8420095 | 0.90 | KDM1A (0.43) | KAT6AMALT1GAAKDM1AMAOA | |
| SCHEMBL8423899 | 0.90 | KDM1A (0.43) | KAT6AMALT1GAAKDM1AMAOA | |
| SCHEMBL8641119 | 0.90 | AURKA (0.46) | KAT6AMALT1GAAKDM1AMAOA | |
| SCHEMBL8421776 | 0.89 | KDM1A (0.47) | KAT6AMALT1GAAKDM1AMAOA | |
| SCHEMBL8423597 | 0.87 | KAT6A (0.42) | KAT6AMALT1KDM1AMAOAAURKA | |
| SCHEMBL8421734 | 0.87 | KDM1A (0.43) | KAT6AMALT1GAAKDM1AMAOA | |
| SCHEMBL8422282 | 0.87 | KDM1A (0.43) | KAT6AMALT1KDM1AMAOAAURKA | |
| SCHEMBL8420734 | 0.87 | MALT1 (0.43) | KAT6AMALT1GAAKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |