Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424340 | 0.88 | OPRL1 (0.51) | OPRL1OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL8422440 | 0.83 | SLC6A2 (0.41) | MEN1ALDH1A1LMNAKMT2AGRIN2B | |
| SCHEMBL8425640 | 0.81 | TACR1 (0.41) | OPRL1OPRD1OPRK1MEN1ALDH1A1 | |
| SCHEMBL8422264 | 0.77 | HTR1D (0.57) | MEN1LMNAKMT2ASIGMAR1 | |
| SCHEMBL8425616 | 0.77 | HTR1D (0.45) | ALDH1A1LMNASIGMAR1 | |
| SCHEMBL8425620 | 0.77 | DRD2 (0.41) | DRD2DRD3DRD4SIGMAR1SLC6A2 | |
| SCHEMBL14279749 | 0.76 | TSHR (0.49) | OPRM1MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL14279693 | 0.73 | KMT2A (0.47) | OPRM1MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL27820393 | 0.73 | SIGMAR1 (0.46) | OPRM1MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL240629 | 0.73 | OPRL1 (0.73) | OPRL1OPRM1OPRD1OPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |