Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159385 | 0.76 | L3MBTL1 (0.37) | TACR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6160860 | 0.74 | TACR2 (0.62) | TACR2TACR1 | |
| SCHEMBL6159549 | 0.73 | TACR2 (0.41) | TACR2 | |
| SCHEMBL6160308 | 0.71 | TSHR (0.35) | TACR2 | |
| Hydrochloric Acid SCHEMBL8425482 | 0.71 | SLC6A2 (0.34) | TACR2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8425483 | 0.69 | MCHR1 (0.33) | TACR2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6158780 | 0.67 | TACR2 (0.44) | TACR2 | |
| Hydrochloric Acid SCHEMBL6159104 | 0.61 | TACR2 (0.55) | TACR2TACR1 | |
| SCHEMBL8425245 | 0.61 | ADRA1D (0.39) | TACR2TACR1 | |
| SCHEMBL6158768 | 0.61 | CA12 (0.42) | TACR2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889024-A | Substituted heterocycles | ZENECA LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |