SCHEMBL8425355

SCHEMBL8425355

CCC1CCC(CC)C(=O)C1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.36
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10267604 0.85 INPP5A (0.38) NOS3NOS1NOS2
SCHEMBL28863019 0.79 KAT6A (0.32) NOS3NOS1NOS2
SCHEMBL3477821 0.77 TLR4 (0.35) LMNA
SCHEMBL3214493 0.77
SCHEMBL5206378 0.76 NOS3 (0.35) NOS3NOS1NOS2HTT
SCHEMBL13283943 0.76 NOS3 (0.35) NOS3NOS1NOS2HTT
Hydrochloric Acid SCHEMBL6069035 0.75
SCHEMBL25937413 0.75 LMNA (0.33) LMNA
SCHEMBL13284120 0.72 NOS3 (0.33) NOS3NOS1NOS2
SCHEMBL27569383 0.72 TLR4 (0.36) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020010494-A1 FUSED CYCLOALKANE FUEL AND PHOTOCATALYTIC PREPARATION METHOD THEREOF 天津大学 2020-01-16 WO disclosed
US-5961954-A Chealators of type XN1 S1 X1 for radioactive isotopes, their metal complexes and their diagnostic and therapeutical uses INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) 1999-10-05 US disclosed