Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427222 | 0.88 | ALDH1A1 (0.48) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL8432299 | 0.86 | HTR6 (0.46) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL483675 | 0.84 | NPC1 (0.51) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18396730 | 0.84 | KMT2A (0.41) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3156650 | 0.83 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2TSHRCYP2C19 | |
| SCHEMBL8425426 | 0.82 | NPC1 (0.50) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18595786 | 0.81 | HPGD (0.48) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5789493 | 0.81 | PKM (0.49) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5791554 | 0.81 | MAOB (0.44) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL15618875 | 0.81 | NPC1 (0.47) | HPGDNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316988-A | Preparation method of linezolid injection degradation impurity | 重庆常捷医药有限公司 | 2017-01-11 | — | — | CN | disclosed |
| US-5990309-A | 2-chloro-5-fluoro-4-morpholinonitrobenzene and 2-chloro-5-fluoro-4-morpholinoaniline | CLARIANT GMBH (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5917037-A | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | disclosed |
| US-5917036-A | Process for the preparation of N-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | disclosed |