Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422440 | 0.90 | SLC6A2 (0.41) | MAPTKMT2ALMNAMEN1GRIN2B | |
| SCHEMBL8425473 | 0.83 | HTR1D (0.52) | MAPTGAAKMT2ALMNAMEN1 | |
| SCHEMBL8423851 | 0.83 | HTR1D (0.59) | MAPTKMT2ALMNAMEN1HTR1D | |
| SCHEMBL8425548 | 0.83 | OPRL1 (0.47) | — | |
| SCHEMBL8424340 | 0.82 | OPRL1 (0.51) | MAPTKMT2ALMNAMEN1GRIN2B | |
| SCHEMBL8425640 | 0.79 | TACR1 (0.41) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL667793 | 0.78 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1HTR1D | |
| SCHEMBL11094660 | 0.75 | MAPT (0.54) | MAPTGAAKMT2ALMNAMEN1 | |
| SCHEMBL8520559 | 0.74 | DRD2 (0.38) | LMNA | |
| SCHEMBL8422264 | 0.74 | HTR1D (0.57) | KMT2ALMNAMEN1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |