Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27523224 | 0.88 | ALDH1A1 (0.55) | GUSBALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8269541 | 0.86 | L3MBTL1 (0.65) | HIF1AKMT2AGAAHSD17B1HSD17B2 | |
| SCHEMBL8425835 | 0.84 | MEN1 (0.56) | GUSBALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7015594 | 0.82 | GUSB (0.66) | GUSBALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28270327 | 0.81 | GUSB (0.56) | GUSBALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15660019 | 0.81 | GUSB (0.56) | GUSBALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8422362 | 0.78 | SMN1; SMN2 (0.72) | GUSBALDH1A1KMT2AGAAMEN1 | |
| SCHEMBL8426004 | 0.75 | GAA (0.57) | GUSBKMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL15658306 | 0.75 | GUSB (0.56) | GUSBALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15232992 | 0.74 | PKM (0.50) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | GUSB 218/4885ALDH1A1 3287/4885CYP1A2 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.