Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508397 | 0.80 | PNMT (0.48) | PNMTADRA2AGRIN2BADRA2BADRA2C | |
| SCHEMBL8425944 | 0.80 | PNMT (0.38) | PNMTADRA2AGRIN2BFFAR4FFAR1 | |
| SCHEMBL8424903 | 0.80 | PNMT (0.38) | PNMTADRA2AGRIN2BFFAR4FFAR1 | |
| SCHEMBL8424902 | 0.80 | PNMT (0.38) | PNMTADRA2AGRIN2BFFAR4FFAR1 | |
| SCHEMBL8425206 | 0.79 | GRIN2B (0.41) | GRIN2BDRD2DRD3FFAR4FFAR1 | |
| SCHEMBL7390944 | 0.78 | GRIN2B (0.41) | PNMTADRA2AGRIN2BTLR9ADRA2B | |
| SCHEMBL16650443 | 0.78 | PNMT (0.46) | PNMTADRA2AGRIN2BCRHBPCRHR2 | |
| SCHEMBL6492849 | 0.77 | ITGB3 (0.50) | PNMTADRA2AGRIN2BFFAR4FFAR1 | |
| SCHEMBL6493305 | 0.77 | ITGB3 (0.50) | PNMTADRA2AGRIN2BFFAR4FFAR1 | |
| SCHEMBL8428771 | 0.76 | CA2 (0.46) | ADRA2AHTR1AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925662-A | OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-07-20 | — | — | US | disclosed |