Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 6/20 | 0.70 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.65 |
| ▸ | P2RY11 | Q96G91 | 5/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 5/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.60 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.60 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450811 | 0.90 | RNASEL (0.85) | RNASELP2RY1P2RY11CA5ANT5E | |
| SCHEMBL26244974 | 0.90 | RNASEL (0.85) | RNASELP2RY1P2RY11CA5ANT5E | |
| SCHEMBL1469233 | 0.89 | RNASEL (0.56) | RNASELP2RY1P2RY11CA5ANT5E | |
| SCHEMBL1469227 | 0.89 | RNASEL (0.56) | RNASELP2RY1P2RY11CA5ANT5E | |
| SCHEMBL8862428 | 0.88 | P2RY1 (0.63) | P2RY1P2RY11CA5ANT5EADORA3 | |
| SCHEMBL8862435 | 0.87 | P2RY1 (0.62) | P2RY1P2RY11CA5ANT5EADORA3 | |
| SCHEMBL8862433 | 0.87 | P2RY1 (0.62) | P2RY1P2RY11CA5ANT5EADORA3 | |
| SCHEMBL30055318 | 0.87 | RNASEL (0.87) | RNASELP2RY1P2RY11ENPP1P2RY12 | |
| SCHEMBL29936666 | 0.86 | ADORA3 (0.78) | RNASELCA5ANT5EADORA3ADORA1 | |
| SCHEMBL8622533 | 0.86 | ADORA3 (0.78) | RNASELCA5ANT5EADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579643-A1 | ATP ANALOGUES | FISONS plc (GB) | 1994-01-26 | — | — | EP | claimed |
| WO-1992017488-A1 | ATP ANALOGUES | FISONS PLC (GB) | 1992-10-15 | — | — | WO | claimed |
| EP-0508687-A1 | ATP analogues | Astra Pharmaceuticals Limited (GB) | 1992-10-14 | — | — | EP | claimed |
| US-5955447-A | ADMINISTERING AS ANTICOAGULANT; TREATING CARDIOVASCULAR DISORDERS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |
| US-5721219-A | ANTICOAGULANTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-02-24 | — | — | US | disclosed |
| EP-0683789-B1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMA PROD (GB) | 1997-11-05 | — | — | EP | disclosed |
| US-5654285-A | ADP and ATP analogues, process for making and administration to inhibit ADP-induced platelet aggregation | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-08-05 | — | — | US | disclosed |
| EP-0683789-A1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | Astra Pharmaceuticals Limited (GB) | 1995-11-29 | — | — | EP | disclosed |
| EP-0508687-B1 | ATP analogues | FISONS PLC (GB) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994018216-A1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMACEUTICALS LIMITED (GB) | 1994-08-18 | — | — | WO | disclosed |
| EP-0579643-A1 | ATP ANALOGUES | FISONS plc (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017488-A1 | ATP ANALOGUES | FISONS PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0508687-A1 | ATP analogues | Astra Pharmaceuticals Limited (GB) | 1992-10-14 | — | — | EP | disclosed |