SCHEMBL1469233

SCHEMBL1469233

Cc1nc(O)c2ncn([C@@H]3O[C@H](COP(O)(O)=S)C(O)C3O)c2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 6/20 0.56
NT5E P21589 3/20 0.55
P2RY1 P47900 3/20 0.54
P2RY11 Q96G91 3/20 0.54
CA5A P35218 1/20 0.52
IMPDH2 P12268 4/20 0.52
IMPDH1 P20839 1/20 0.52
TAS1R3 Q7RTX0 2/20 0.50
TAS1R1 Q7RTX1 2/20 0.50
DNPH1 O43598 1/20 0.50
PRKAB2 O43741 1/20 0.50
TRPM2 O94759 1/20 0.50
LDHA P00338 1/20 0.50
ADRB2 P07550 1/20 0.50
FBP1 P09467 1/20 0.50
SRC P12931 1/20 0.50
ADORA1 P30542 1/20 0.50
P2RY2 P41231 1/20 0.50
PRKAG1 P54619 1/20 0.50
PRKAA2 P54646 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469227 1.00 RNASEL (0.56) RNASELNT5EP2RY1P2RY11CA5A
SCHEMBL8426440 0.89 RNASEL (0.70) RNASELNT5EP2RY1P2RY11CA5A
SCHEMBL16619900 0.86 ADORA3 (0.64) RNASELNT5EIMPDH2IMPDH1ADORA1
SCHEMBL5690848 0.84 P2RY1 (0.63) NT5EP2RY1P2RY11TAS1R3TAS1R1
SCHEMBL1898711 0.82 LMNA (0.62) NT5EADORA1
SCHEMBL1898718 0.82 LMNA (0.62) NT5EADORA1
Phosphoric Acid SCHEMBL30965379 0.82 P2RY1 (0.66) NT5EP2RY1P2RY11TAS1R3TAS1R1
SCHEMBL8862433 0.81 P2RY1 (0.62) NT5EP2RY1P2RY11CA5A
SCHEMBL188740 0.80 CA5A (0.68) RNASELNT5EP2RY1P2RY11CA5A
SCHEMBL24049291 0.79 NT5E (0.54) NT5EP2RY1P2RY11CA5ATAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042537-B2 Methods of using low dose volume B-cell epitope compositions for inducing an antibody immune response in human subjects BioVaxys Inc. (US) 2024-07-23 US disclosed
US-11717563-B2 Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2023-08-08 US disclosed
US-20220347296-A1 METHODS OF USING LOW DOSE VOLUME B-CELL EPITOPE COMPOSITIONS FOR INDUCING AN ANTIBODY IMMUNE RESPONSE IN HUMAN SUBJECTS IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2022-11-03 US disclosed
US-11406705-B2 Methods of using low dose volume B-cell epitope compositions for inducing an antibody immune response in human subjects IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2022-08-09 US disclosed
US-20220143165-A1 VACCINE COMPOSITIONS COMPRISING AN AMPHIPATHIC COMPOUND, A NEOANTIGEN AND A HYDROPHOBIC CARRIER, AND METHODS OF USE THEREOF IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2022-05-12 US disclosed
US-11260116-B2 Vaccine compositions comprising an amphipathic compound, a neoantigen and a hydrophobic carrier, and methods of use thereof IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2022-03-01 US disclosed
US-20220001010-A1 ADJUVANTING SYSTEMS AND WATER-FREE VACCINE COMPOSITIONS COMPRISING A POLYI:C POLYNUCLEOTIDE ADJUVANT AND A LIPID-BASED ADJUVANT IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2022-01-06 US disclosed
US-11160861-B2 Adjuvanting systems and water-free vaccine compositions comprising a polyI:C polynucleotide adjuvant and a lipid-based adjuvant IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2021-11-02 US disclosed
US-20190290743-A1 Compositions Comprising Liposomes, An Antigen, A Polynucleotide and A Carrier Comprising a Continuous Phase of a Hydrophobic Substance IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2019-09-26 US disclosed
EP-3518963-A1 METHODS OF USING LOW DOSE VOLUME B-CELL EPITOPE COMPOSITIONS FOR INDUCING AN ANTIBODY IMMUNE RESPONSE IN HUMAN SUBJECTS ImmunoVaccine Technologies Inc. (CA) 2019-08-07 EP disclosed
US-20190151428-A1 Vaccine Compositions Comprising an Amphipathic Compound, a Neoantigen and a Hydrophobic Carrier, and Methods of Use Thereof IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2019-05-23 US disclosed
EP-3452083-A1 VACCINE COMPOSITIONS COMPRISING AN AMPHIPATHIC COMPOUND, A NEOANTIGEN AND A HYDROPHOBIC CARRIER, AND METHODS OF USE THEREOF ImmunoVaccine Technologies Inc. (CA) 2019-03-13 EP disclosed
US-20180339039-A1 Adjuvanting Systems and Water-Free Vaccine Compositions Comprising a PolyI:C Polynucleotide Adjuvant and a Lipid-based Adjuvant IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2018-11-29 US disclosed
EP-3377099-A1 ADJUVANTING SYSTEMS AND WATER-FREE VACCINE COMPOSITIONS COMPRISING A POLYI:C POLYNUCLEOTIDE ADJUVANT AND A LIPID-BASED ADJUVANT ImmunoVaccine Technologies Inc. (CA) 2018-09-26 EP disclosed
WO-2018058230-A1 METHODS OF USING LOW DOSE VOLUME B-CELL EPITOPE COMPOSITIONS FOR INDUCING AN ANTIBODY IMMUNE RESPONSE IN HUMAN SUBJECTS IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2018-04-05 WO disclosed
WO-2017190242-A1 VACCINE COMPOSITIONS COMPRISING AN AMPHIPATHIC COMPOUND, A NEOANTIGEN AND A HYDROPHOBIC CARRIER, AND METHODS OF USE THEREOF IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2017-11-09 WO disclosed
EP-2296696-B1 COMPOSITIONS COMPRISING LIPOSOMES, AN ANTIGEN, A POLYNUCLEOTIDE AND A CARRIER COMPRISING A CONTINUOUS PHASE OF A HYDROPHOBIC SUBSTANCE IMMUNOVACCINE TECHNOLOGIES INC (CA) 2014-08-27 EP disclosed
US-20110070298-A1 Compositions Comprising Liposomes, An Antigen, A Polynucleotide and A Carrier Comprising a Continuous Phase of a Hydrophobic Substance IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2011-03-24 US disclosed
EP-2296696-A1 COMPOSITIONS COMPRISING LIPOSOMES, AN ANTIGEN, A POLYNUCLEOTIDE AND A CARRIER COMPRISING A CONTINUOUS PHASE OF A HYDROPHOBIC SUBSTANCE ImmunoVaccine Technologies Inc. (CA) 2011-03-23 EP disclosed
WO-2009146523-A1 COMPOSITIONS COMPRISING LIPOSOMES, AN ANTIGEN, A POLYNUCLEOTIDE AND A CARRIER COMPRISING A CONTINUOUS PHASE OF A HYDROPHOBIC SUBSTANCE IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11260116-B2 Vaccine compositions comprising an amphipathic compound, a neoantigen and a hydrophobic carrier, and methods of use thereof TP53, HLA-DRB1, CD74 RNASEL 3450/4885NT5E 3354/4885P2RY1 4611/4885
US-20190151428-A1 Vaccine Compositions Comprising an Amphipathic Compound, a Neoantigen and a Hydrophobic Carrier, and Methods of Use Thereof TP53, HLA-DRB1, CD74 RNASEL 3450/4885NT5E 3354/4885P2RY1 4611/4885
US-20220143165-A1 VACCINE COMPOSITIONS COMPRISING AN AMPHIPATHIC COMPOUND, A NEOANTIGEN AND A HYDROPHOBIC CARRIER, AND METHODS OF USE THEREOF TP53, HLA-DRB1, CD74 RNASEL 3450/4885NT5E 3354/4885P2RY1 4611/4885
US-11160861-B2 Adjuvanting systems and water-free vaccine compositions comprising a polyI:C polynucleotide adjuvant and a lipid-based adjuvant TLR3, PLA2G2C, TLR9 RNASEL 305/4885NT5E 631/4885P2RY1 1464/4885
US-20220001010-A1 ADJUVANTING SYSTEMS AND WATER-FREE VACCINE COMPOSITIONS COMPRISING A POLYI:C POLYNUCLEOTIDE ADJUVANT AND A LIPID-BASED ADJUVANT TLR3, PLA2G2C, TLR9 RNASEL 305/4885NT5E 631/4885P2RY1 1464/4885
US-20180339039-A1 Adjuvanting Systems and Water-Free Vaccine Compositions Comprising a PolyI:C Polynucleotide Adjuvant and a Lipid-based Adjuvant TLR3, PLA2G2C, TLR9 RNASEL 305/4885NT5E 631/4885P2RY1 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.