Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853292 | 0.98 | HTT (0.37) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL27897257 | 0.81 | CA12 (0.53) | HTTGAALIPELMNACA12 | |
| SCHEMBL8396990 | 0.80 | HTT (0.46) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL1147606 | 0.79 | CYP2D6 (0.45) | HTTL3MBTL1LIPEPOLBNPC1 | |
| SCHEMBL5321367 | 0.78 | HTT (0.40) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL9872789 | 0.78 | HTT (0.45) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL6123494 | 0.77 | HTT (0.45) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL637498 | 0.77 | HTT (0.45) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| SCHEMBL13574319 | 0.77 | HTT (0.36) | HTTL3MBTL1ALDH1A1KDM4ETP53 | |
| Benzene SCHEMBL7370712 | 0.75 | GNAI3 (0.41) | HTTL3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541013-B2 | Amphiphilic terpolymer having pH-sensitive hydrophobic units derived from a polyunsaturated fatty acid (9,12-Octadecadienoic Acid), hydrophilic units with polar groups (acrylic acid), and temperature-sensitive units (acryloylpiperidine), useful for drug delivery | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-09-24 | — | — | US | claimed |
| US-8512757-B2 | Micelles for drug delivery | AGENCY FOR SCIENCE, TECHOLOGY AND RESEARCH (SG) | 2013-08-20 | — | — | US | claimed |
| EP-1765894-B9 | NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS | AGENCY SCIENCE TECH & RES (SG) | 2012-08-01 | — | — | EP | claimed |
| EP-1765894-B1 | NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS | AGENCY SCIENCE TECH & RES (SG) | 2012-03-28 | — | — | EP | claimed |
| US-20100159019-A1 | Micelles For Drug Delivery | AGENCY OF SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-06-24 | — | — | US | claimed |
| CN-100582130-C | Novel temperature and PH sensitive copolymers | AGENCY SCIENCE TECH & RES | 2010-01-20 | — | — | CN | claimed |
| EP-2035488-A1 | MICELLES FOR DRUG DELIVERY | Agency for Science, Technology and Research (SG) | 2009-03-18 | — | — | EP | claimed |
| US-20080182959-A1 | Novel Temperature and pH Sensitive Copolymers | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2008-07-31 | — | — | US | claimed |
| WO-2008004978-A1 | MICELLES FOR DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-01-10 | — | — | WO | claimed |
| US-7316816-B2 | Temperature and pH sensitive copolymers | AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH (SG) | 2008-01-08 | — | — | US | claimed |
| CN-1984935-A | Novel temperature and PH sensitive copolymers | AGENCY SCIENCE TECH & RES (SG) | 2007-06-20 | — | — | CN | claimed |
| EP-1765894-A1 | NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS | Agency for Science, Technology and Research (SG) | 2007-03-28 | — | — | EP | claimed |
| WO-2005121196-A1 | NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2005-12-22 | — | — | WO | claimed |
| US-20050277739-A1 | Amphiphilic terpolymer having pH-sensitive hydrophobic units derived from a polyunsaturated fatty acid (9,12-Octadecadienoic Acid), hydrophilic units with polar groups (acrylic acid), and temperature-sensitive units (acryloylpiperidine); lower critical solution temperature decreases as pH decreases | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2005-12-15 | — | — | US | claimed |
| US-9987221-B2 | Injectable hydrogel compositions | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2018-06-05 | — | — | US | disclosed |
| US-9632222-B2 | Method for manufacturing a color filter, color filter and solid-state imaging device | FUJIFILM CORPORATION (JP) | 2017-04-25 | — | — | US | disclosed |
| US-9625618-B2 | Optical member set and solid-state imaging element using the same | FUJIFILM CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| US-20030146965-A1 | AQUEOUS ALKALINE SOLUBLE POLYMER HAVING CARBON-CARBON DOUBLE BOND SIDE CHAINS, LIGHT-HEAT CONVERTING AGENT AND FREE RADICAL INITIATOR; PLANOGRAPHIC PRINTING PLATE; PRINTING RESISTANCE; STORAGE STABILITY; STRENGTH OF IMAGE PORTION | FUJI PHOTO FILM CO., LTD. | 2003-08-07 | — | — | US | disclosed |
| EP-1285751-A2 | Image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-20020029968-A1 | Dynamic coating with linear polymer mixture for electrophoresis | ACLARA BIOSCIENCES, INC. | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100159019-A1 | Micelles For Drug Delivery | ABCC1, MTDH, CHMP4B | HTT 595/4885L3MBTL1 600/4885ALDH1A1 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.