SCHEMBL8427263

SCHEMBL8427263

Cc1cc(-c2ccc(S(=O)(=O)c3cc(C)ccc3C)cc2S(=O)(=O)c2cc(C)ccc2C)c(C)c(S(=O)(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2N P61088 1/20 0.37
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 7/20 0.35
GAA P10253 3/20 0.35
PKM P14618 1/20 0.35
RAPGEF4 Q8WZA2 2/20 0.35
NAMPT P43490 1/20 0.35
TSHR P16473 1/20 0.35
TP53 P04637 1/20 0.34
HSD17B13 Q7Z5P4 1/20 0.34
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 3/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
F2 P00734 1/20 0.33
XBP1 P17861 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059409 0.86 ALDH1A1 (0.41) UBE2NKMT2AALDH1A1GAAPKM
SCHEMBL8431095 0.82 UBE2N (0.36) UBE2NKMT2AALDH1A1GAAPKM
SCHEMBL8064348 0.75 POLB (0.43) KMT2AALDH1A1GAANAMPTLMNA
SCHEMBL6211399 0.75 GAA (0.60) UBE2NKMT2AALDH1A1GAAPKM
SCHEMBL30810186 0.73 ALDH1A1 (0.50) UBE2NKMT2AALDH1A1GAATSHR
SCHEMBL8064351 0.73 HSD17B13 (0.46) KMT2AALDH1A1TP53HSD17B13MAPT
SCHEMBL13721233 0.73 GAA (0.52) KMT2AALDH1A1GAAPKMRAPGEF4
SCHEMBL12301831 0.73 GAA (0.57) KMT2AALDH1A1GAAPKMRAPGEF4
SCHEMBL12450093 0.72 LMNA (0.48) ALDH1A1GAAPKMTSHRLMNA
SCHEMBL11127859 0.72 GAA (0.60) UBE2NKMT2AALDH1A1GAARAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP claimed