SCHEMBL8059409

SCHEMBL8059409

Cc1ccc(C)c(S(=O)(=O)c2ccc(-c3ccccc3S(=O)(=O)O)c(S(=O)(=O)c3cc(C)ccc3C)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 3/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 1/20 0.41
F2 P00734 1/20 0.41
XBP1 P17861 1/20 0.41
UBE2N P61088 1/20 0.38
NAMPT P43490 1/20 0.38
ELANE P08246 1/20 0.37
MEN1 O00255 2/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HSD11B1 P28845 1/20 0.36
GAA P10253 2/20 0.36
G6PD P11413 1/20 0.36
CNR2 P34972 1/20 0.36
APAF1 O14727 1/20 0.36
PKM P14618 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059453 0.86 GAA (0.47) ALDH1A1MAPTHTTKDM4ETDP1
SCHEMBL8431095 0.86 UBE2N (0.36) ALDH1A1KMT2AMAPTHTTKDM4E
SCHEMBL8427263 0.86 UBE2N (0.37) ALDH1A1KMT2AMAPTHTTKDM4E
SCHEMBL8059442 0.85 ALDH1A1 (0.48) ALDH1A1KMT2AMAPTHTTTDP1
SCHEMBL8064348 0.84 POLB (0.43) ALDH1A1KMT2AMAPTHTTKDM4E
SCHEMBL8046886 0.79 HTR6 (0.45) ALDH1A1KMT2AMAPTHTTHSD11B1
SCHEMBL2761135 0.78 ELANE (0.47) ALDH1A1KMT2AMAPTHTTKDM4E
SCHEMBL5674095 0.78 ELANE (0.47) ALDH1A1KMT2AMAPTHTTKDM4E
SCHEMBL6211399 0.76 GAA (0.60) ALDH1A1KMT2AMAPTHTTUBE2N
SCHEMBL6215926 0.75 L3MBTL1 (0.53) ALDH1A1KMT2AMAPTHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed