Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.58 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.53 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8424679 | 0.92 | RAPGEF3 (0.51) | RAPGEF3KAT6AMEP1BPLAUALDH1A1 | |
| SCHEMBL8425825 | 0.88 | MAPT (0.60) | RAPGEF3KAT6AMEP1BPLAUALDH1A1 | |
| SCHEMBL6848743 | 0.83 | KAT6A (0.63) | KAT6AALDH1A1POLBCTSSL3MBTL1 | |
| SCHEMBL8428222 | 0.83 | RAPGEF3 (0.54) | RAPGEF3KAT6AMEP1BPLAUALDH1A1 | |
| Hydrochloric Acid SCHEMBL27487670 | 0.82 | KAT6A (0.61) | KAT6AALDH1A1POLBCTSSL3MBTL1 | |
| SCHEMBL5171144 | 0.79 | KMT2A (0.59) | MEP1BALDH1A1POLBNPSR1KMT2A | |
| SCHEMBL7598374 | 0.78 | NPC1 (0.47) | KAT6AMEP1BALDH1A1POLBCTSS | |
| SCHEMBL3097522 | 0.76 | RAPGEF3 (0.57) | RAPGEF3KAT6APLAUALDH1A1KMT2A | |
| SCHEMBL8425827 | 0.76 | RAPGEF3 (0.57) | RAPGEF3KAT6APLAUALDH1A1KMT2A | |
| SCHEMBL8428170 | 0.76 | KAT6A (0.60) | RAPGEF3KAT6APLAUALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |