Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.59 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428166 | 0.88 | RAPGEF3 (0.58) | RAPGEF3KAT6AALDH1A1MEP1BPLAU | |
| SCHEMBL4173740 | 0.84 | MEP1B (0.67) | MAPTALDH1A1MEP1BPOLBNPSR1 | |
| SCHEMBL8428222 | 0.84 | RAPGEF3 (0.54) | MAPTRAPGEF3KAT6AALDH1A1MEP1B | |
| Trifluoroacetic Acid SCHEMBL8424679 | 0.83 | RAPGEF3 (0.51) | MAPTRAPGEF3KAT6AALDH1A1MEP1B | |
| SCHEMBL6438335 | 0.83 | ALDH1A1 (0.69) | KAT6AALDH1A1APEX1CTSS | |
| SCHEMBL4175747 | 0.82 | MEP1B (0.75) | MAPTKAT6AALDH1A1APEX1MEP1B | |
| SCHEMBL3905853 | 0.77 | APEX1 (0.57) | KAT6AALDH1A1APEX1MEP1BPLAU | |
| SCHEMBL8428170 | 0.77 | KAT6A (0.60) | MAPTRAPGEF3KAT6AALDH1A1PLAU | |
| SCHEMBL8425827 | 0.77 | RAPGEF3 (0.57) | MAPTRAPGEF3KAT6AALDH1A1PLAU | |
| SCHEMBL8973399 | 0.77 | POLB (0.56) | ALDH1A1APEX1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |