Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905853 | 0.87 | APEX1 (0.57) | KAT6AALDH1A1MMP1MEP1BCTSS | |
| SCHEMBL6848743 | 0.85 | KAT6A (0.63) | KAT6AALDH1A1CTSSF10F2 | |
| SCHEMBL6850445 | 0.84 | MEP1B (0.62) | NPC1ALDH1A1MMP1MEP1BF2 | |
| Hydrochloric Acid SCHEMBL27487670 | 0.84 | KAT6A (0.61) | KAT6AALDH1A1CTSSF10F2 | |
| SCHEMBL6791925 | 0.83 | ALDH1A1 (0.57) | NPC1KAT6AALDH1A1MMP1MEP1B | |
| SCHEMBL6850559 | 0.82 | KAT6A (0.61) | KAT6A | |
| SCHEMBL6079464 | 0.80 | ALDH1A1 (0.53) | NPC1KAT6AALDH1A1MMP1CTSS | |
| SCHEMBL7053334 | 0.79 | CYP3A4 (0.54) | ALDH1A1F10TPSAB1POLB | |
| SCHEMBL5729430 | 0.79 | ACACB (0.47) | NPC1KAT6AALDH1A1MMP1MEP1B | |
| SCHEMBL8428166 | 0.78 | RAPGEF3 (0.58) | KAT6AALDH1A1MEP1BCTSSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193382-A1 | Sulfonamide derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-1054005-A1 | SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193382-A1 | Sulfonamide derivatives, their production and use | F12, F11, F2 | NPC1 4444/4885KAT6A 3103/4885ALDH1A1 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.