Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 5/20 | 0.60 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8424682 | 0.92 | KAT6A (0.53) | KAT6ARAPGEF3ALDH1A1MAPTGFER | |
| SCHEMBL8425827 | 0.81 | RAPGEF3 (0.57) | KAT6ARAPGEF3ALDH1A1MAPTPLAU | |
| SCHEMBL8425825 | 0.77 | MAPT (0.60) | KAT6ARAPGEF3ALDH1A1MAPTPLAU | |
| SCHEMBL8428166 | 0.76 | RAPGEF3 (0.58) | KAT6ARAPGEF3ALDH1A1PLAUKMT2A | |
| SCHEMBL2326546 | 0.76 | MEN1 (0.58) | RAPGEF3PLAUKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27504393 | 0.74 | MEN1 (0.56) | RAPGEF3PLAUKMT2AMEN1 | |
| SCHEMBL23832450 | 0.73 | RAPGEF3 (1.00) | RAPGEF3ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29843508 | 0.73 | RAPGEF3 (1.00) | RAPGEF3ALDH1A1MAPTKMT2AMEN1 | |
| Acetamide SCHEMBL8424678 | 0.73 | RAPGEF3 (0.49) | KAT6ARAPGEF3PLAUKMT2AMEN1 | |
| SCHEMBL3101086 | 0.72 | LMNA (0.61) | RAPGEF3PLAUKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |