Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795017 | 0.77 | MAOA (0.33) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL27911540 | 0.76 | LMNA (0.40) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10344557 | 0.75 | MAOA (0.41) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL24012949 | 0.75 | MAOA (0.41) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL1453001 | 0.74 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL5173197 | 0.74 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL343269 | 0.74 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL1713865 | 0.73 | SMN1; SMN2 (0.50) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| Fluoride SCHEMBL1336886 | 0.72 | MAOA (0.48) | MAOAMAOBSMN1; SMN2HSD17B10MAPT | |
| Fluoride SCHEMBL27856329 | 0.72 | MAOA (0.48) | MAOAMAOBSMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856556-A | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |