SCHEMBL27911540

SCHEMBL27911540

C[Si](C)(C)C(O)Sc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
MGLL Q99685 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.37
MAPK1 P28482 4/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TSHR P16473 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428763 0.76 MAOA (0.39) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL95522 0.75 LMNA (0.42) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL4594959 0.72 SMN1; SMN2 (0.43) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL15912538 0.71 KDM4E (0.41) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL5081592 0.71 LMNA (0.40) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL8836724 0.71 L3MBTL1 (0.38) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL1261710 0.70 LMNA (0.46) LMNAALDH1A1SMN1; SMN2L3MBTL1HSD17B10
SCHEMBL1226276 0.70 SMN1; SMN2 (0.41) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT
SCHEMBL6545896 0.70 TDP1 (0.37) LMNASMN1; SMN2L3MBTL1MAPTHPGD
SCHEMBL7219363 0.70 LMNA (0.33) LMNAALDH1A1SMN1; SMN2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104817801-A INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION NIPPON KASEI CHEM 2015-08-05 CN disclosed
CN-102985483-B Inorganic-organic hybrid material, optical material using same, and inorganic-organic composite composition NIPPON KASEI CHEM 2015-06-10 CN disclosed
CN-102985483-A Inorganic-organic hybrid material, optical material using same, and inorganic-organic composite composition NIPPON KASEI CHEM 2013-03-20 CN disclosed