Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494961 | 0.92 | SENP1 (0.62) | PKMSENP1SENP2LMNAALDH1A1 | |
| SCHEMBL7494957 | 0.92 | SENP1 (0.62) | PKMSENP1SENP2LMNAALDH1A1 | |
| SCHEMBL8437247 | 0.89 | LMNA (0.50) | SENP1SENP2LMNANAMPTROCK2 | |
| SCHEMBL8500095 | 0.83 | PPARG (0.59) | SENP1LMNANAMPTROCK2ALDH1A1 | |
| SCHEMBL8428817 | 0.82 | PKM (0.50) | PKMSENP1SENP2LMNANAMPT | |
| SCHEMBL7494303 | 0.81 | SENP1 (0.55) | PKMSENP1SENP2LMNANAMPT | |
| SCHEMBL7494300 | 0.81 | SENP1 (0.55) | PKMSENP1SENP2LMNANAMPT | |
| SCHEMBL8303238 | 0.80 | AKR1C3 (0.49) | PKMLMNAAKR1C3AKR1C2AKR1C4 | |
| SCHEMBL8499211 | 0.79 | LMNA (0.54) | SENP1LMNANAMPTROCK2ALDH1A1 | |
| SCHEMBL7497321 | 0.78 | SENP1 (0.59) | PKMSENP1SENP2LMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |