SCHEMBL8428873

SCHEMBL8428873

O=C1c2ccccc2C(=O)c2c(NCCO)ccc(O)c21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2B Q02880 1/20 0.70
MEN1 O00255 7/20 0.66
KMT2A Q03164 7/20 0.66
BLM P54132 5/20 0.66
LMNA P02545 5/20 0.66
MAPK1 P28482 5/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
TDP1 Q9NUW8 4/20 0.66
NPC1 O15118 3/20 0.66
RAB9A P51151 3/20 0.66
RECQL P46063 3/20 0.66
NSD2 O96028 3/20 0.66
USP2 O75604 2/20 0.66
TP53 P04637 2/20 0.66
MTOR P42345 2/20 0.66
EGFR P00533 2/20 0.66
HTT P42858 2/20 0.66
HIF1A Q16665 2/20 0.66
SLC22A2 O15244 1/20 0.66
SLC22A1 O15245 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1426702 0.92 TOP2B (0.81) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL29357976 0.92 TOP2B (0.81) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL18567079 0.91 TOP2B (0.86) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL6661577 0.91 CYP19A1 (0.80) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL6666259 0.90 CYP19A1 (0.73) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL20334357 0.89 NQO1 (0.73) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL497032 0.89 MEN1 (0.81) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL30439813 0.89 MEN1 (0.81) TOP2BMEN1KMT2ABLMLMNA
Mitoxantrone SCHEMBL187688 0.87 MEN1 (0.84) TOP2BMEN1KMT2ABLMLMNA
SCHEMBL8947726 0.87 TOP2B (0.74) TOP2BMEN1KMT2ABLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
EP-3558235-B1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION OREAL (FR) 2021-09-08 EP disclosed
WO-2018115337-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2018-06-28 WO disclosed
US-5942292-A Spacer for liquid crystal display and liquid crystal display made by using the same KAO CORPORATION (JP) 1999-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 TOP2B 989/4885MEN1 2794/4885KMT2A 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.