Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769013 | 0.93 | LMNA (0.46) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL16604542 | 0.91 | ACE (0.41) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL2494999 | 0.87 | LMNA (0.46) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL28931985 | 0.87 | LMNA (0.46) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL16769014 | 0.87 | LMNA (0.46) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL2460791 | 0.86 | ACE (0.41) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL11216737 | 0.86 | ACE (0.41) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL31453008 | 0.86 | ACE (0.41) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL6225010 | 0.85 | LMNA (0.44) | MEN1KMT2ALMNAPLGPLAT | |
| SCHEMBL11070544 | 0.85 | LMNA (0.44) | MEN1KMT2ALMNAPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756634-A | Liquid one component PU stoving enamels | HUELS AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | claimed |
| US-9795586-B2 | HNF4-α antagonist and use thereof | NATIONAL CANCER CENTER (KR) | 2017-10-24 | — | — | US | disclosed |
| US-9795586-B2 | HNF4-α antagonist and use thereof | NATIONAL CANCER CENTER (KR) | 2017-10-24 | — | — | US | disclosed |
| US-20170189371-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | NATIONAL CANCER CENTER (KR) | 2017-07-06 | — | — | US | disclosed |
| US-20170189371-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | NATIONAL CANCER CENTER (KR) | 2017-07-06 | — | — | US | disclosed |
| US-20160193238-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | NATIONAL CANCER CENTER (KR) | 2016-07-07 | — | — | US | disclosed |
| US-20160193238-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | NATIONAL CANCER CENTER (KR) | 2016-07-07 | — | — | US | disclosed |
| EP-0761705-B1 | Liquid one-component polyurethane storing lacquers | DEGUSSA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5756634-A | Liquid one component PU stoving enamels | HUELS AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0761705-A1 | Liquid one-component polyurethane storing lacquers | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-03-12 | — | — | EP | disclosed |
| US-4430474-A | POLYESTERURETHANES CONTAINING URETIDIONE AND ISOPHORONE GROUPS; STORAGE STABILITY; COATINGS | CHEMISCHE WERKE HUELS AG (DE) | 1984-02-07 | — | — | US | disclosed |
| EP-0001468-B1 | POWDERED COATING PRODUCTS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CHEMISCHE WERKE HÜLS AG (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0001467-B1 | STOVING LACQUERS HAVING AN EXTENDED POT LIFE ON THE BASIS OF POLYISOCYANATE MASKED WITH IMIDAZOLINES | CHEMISCHE WERKE HÜLS AG (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4255551-A | EXTRUDING WITH A SOLID HYDROXYL GROUP-CONTAINING POLYESTER, COOLING, MILLING, SCREENING; STORAGE STABILITY | CHEMISCHE WERKE HULS AG (DE) | 1981-03-10 | — | — | US | disclosed |
| US-4242248-A | WEATHER RESISTANT COIL COATING | CHEMISCHE WERKE HULS AG (DE) | 1980-12-30 | — | — | US | disclosed |
| US-4151152-A | POLYESTERURETHANES, SHELF LIFE | VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) | 1979-04-24 | — | — | US | disclosed |
| EP-0001468-A1 | Powdered coating products, process for their preparation and their use | CHEMISCHE WERKE HÜLS AG (DE) | 1979-04-18 | — | — | EP | disclosed |
| EP-0001467-A1 | Stoving lacquers having an extended pot life on the basis of polyisocyanate masked with imidazolines | CHEMISCHE WERKE HÜLS AG (DE) | 1979-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189371-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | HNF4A, TCF4, WNT3A | MEN1 4787/4885KMT2A 1796/4885LMNA 4194/4885 |
| US-20160193238-A1 | HNF4-alpha ANTAGONIST AND USE THEREOF | HNF4A, TCF4, WNT3A | MEN1 4787/4885KMT2A 1796/4885LMNA 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.