Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429251 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL167473 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL5603396 | 0.82 | CTSB (0.32) | ALDH1A1 | |
| SCHEMBL9506387 | 0.80 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL30492736 | 0.79 | — | — | |
| SCHEMBL8852486 | 0.78 | — | — | |
| SCHEMBL31357273 | 0.77 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL6889580 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8848418 | 0.76 | — | — | |
| SCHEMBL9508777 | 0.74 | PDK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621439-B1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC (US) | 2022-11-30 | — | — | EP | disclosed |
| US-11363816-B2 | 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyramidine-4-carboxylates and their use as herbicides | CORTEVA AGRISCIENCE LLC (US) | 2022-06-21 | — | — | US | disclosed |
| EP-3621439-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-20200068888-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRAMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2020-03-05 | — | — | US | disclosed |
| WO-2018208582-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2018-11-15 | — | — | WO | disclosed |
| US-5973229-A | ISOLATED, PURIFIED PROTEIN ENCODING CDNA; TO ALTER PLANT'S SENSITIVITY TO CERTAIN HERBICIDES | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1999-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11363816-B2 | 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyramidine-4-carboxylates and their use as herbicides | DDT, PFAS, P2RX6 | SMN1; SMN2 3190/4885MEN1 3893/4885ALDH1A1 544/4885 |
| US-20200068888-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRAMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, PFAS, P2RX6 | SMN1; SMN2 3190/4885MEN1 3893/4885ALDH1A1 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.