Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709583 | 0.92 | BRD4 (0.64) | GRM5BRD4KMT2AMEN1POLB | |
| SCHEMBL19689370 | 0.88 | BRD4 (0.72) | GRM5BRD4KMT2AMEN1POLB | |
| SCHEMBL20346175 | 0.88 | BRD4 (0.63) | GRM5BRD4KMT2AMEN1POLB | |
| SCHEMBL10641093 | 0.86 | BRD4 (0.65) | GRM5BRD4KMT2AMEN1POLB | |
| SCHEMBL22310425 | 0.86 | BRD4 (0.61) | BRD4KMT2AMEN1POLBMAPK1 | |
| SCHEMBL16597893 | 0.84 | BRD4 (0.56) | GRM5BRD4KMT2AMEN1POLB | |
| SCHEMBL16598017 | 0.83 | BRD4 (0.58) | GRM5BRD4KMT2AMEN1POLB | |
| SCHEMBL14010059 | 0.81 | BRD4 (0.60) | BRD4KMT2AMEN1POLBMAPK1 | |
| SCHEMBL13302880 | 0.81 | MGLL (0.65) | GRM5BRD4KMT2AMEN1NR1H3 | |
| SCHEMBL3408445 | 0.81 | KMT2A (0.66) | BRD4KMT2AMEN1NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892061-A | REACTING A MONO- OR POLYCARBOXYLIC ACID WITH A MONO- OR POLYAMIDE IN THE PRESENCE OF A HALOIMINIUM SALT AND BASE; CATALYST SELECTIVITY | MITSUI CHEMICALS, INC. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0846714-A1 | Preparation process of isoimide | Mitsui Chemicals, Inc. (JP) | 1998-06-10 | — | — | EP | disclosed |