Sugi Predict

Sugi Predict / Compounds / SCHEMBL8430617

SCHEMBL8430617

SCHEMBL8430617

C#CCOC(=O)CCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.47
▸ TAAR1 Q96RJ0 1/20 0.47
▸ GSTP1 P09211 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ LMNA P02545 3/20 0.41
▸ EGLN1 Q9GZT9 2/20 0.41
▸ ALKBH5 Q6P6C2 1/20 0.41
▸ SUCNR1 Q9BXA5 1/20 0.41
▸ MAPT P10636 3/20 0.40
▸ CYP2D6 P10635 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ KDM6B O15054 1/20 0.40
▸ KDM5C P41229 1/20 0.40
▸ PHF8 Q9UPP1 1/20 0.40
▸ KDM2A Q9Y2K7 1/20 0.40
▸ NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17695709 0.94 TSHR (0.46) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL27279873 0.94 TSHR (0.46) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL27281476 0.92 TSHR (0.44) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL4446043 0.91 GSTP1 (0.53) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL1483317 0.87 GSTP1 (0.57) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL10476498 0.87 TSHR (0.57) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL10476495 0.85 GSTP1 (0.56) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL12769145 0.84 GSTP1 (0.49) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL27280780 0.82 L3MBTL1 (0.39) TSHRALDH1A1TAAR1GSTP1L3MBTL1
SCHEMBL10011454 0.81 GSTP1 (0.59) TSHRALDH1A1TAAR1GSTP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113061210-B Janus type star polymer with circular polarization fluorescence 合肥工业大学 2022-12-06 — — CN claimed
CN-108743969-B Preparation method of tumor targeting nano-carrier with cell-like cell-penetrating peptide function 合肥工业大学 2021-09-07 — — CN claimed
CN-113061210-A Janus type star polymer with circular polarization fluorescence 合肥工业大学 2021-07-02 — — CN claimed
CN-112071623-A Preparation method of soft magnetic material for high frequency 杭州肄康新材料有限公司 2020-12-11 — — CN claimed
CN-111440254-A Polyrotaxane grafted polyisonitrile and preparation method and application thereof 合肥工业大学 2020-07-24 — — CN claimed
EP-2479831-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2012-07-25 — — EP claimed
EP-0957684-A1 MICROEMULSION AND METHOD Troy Technology Corporation, Inc. (US) 1999-11-24 — — EP claimed
WO-1998018321-A1 MICROEMULSION AND METHOD TROY TECHNOLOGY CORPORATION, INC. (US) 1998-05-07 — — WO claimed
US-20240067672-A1 FLAVONE DERIVATIVE FOR TREATING TUMORS AND USE THEREOF SICHUAN FUSHENGYUAN TECHNOLOGY CO., LTD (CN) 2024-02-29 — — US disclosed
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 — — US disclosed
CN-113061210-B Janus type star polymer with circular polarization fluorescence 合肥工业大学 2022-12-06 — — CN disclosed
CN-111040079-B High-crosslinking-degree topological structure self-repairing elastomer and preparation method and application thereof 广东电网有限责任公司 2021-09-10 — — CN disclosed
CN-108743969-B Preparation method of tumor targeting nano-carrier with cell-like cell-penetrating peptide function 合肥工业大学 2021-09-07 — — CN disclosed
CN-113061210-A Janus type star polymer with circular polarization fluorescence 合肥工业大学 2021-07-02 — — CN disclosed
US-7560588-B2 Poly(ethylene glycol) containing chemically disparate endgroups INTEZYNE TECHNOLOGIES, INC. (US) 2009-07-14 — — US disclosed
US-20080207913-A1 Poly(ethylene glycol) containing chemically disparate endgroups INTEZYNE TECHNOLOGIES (US) 2008-08-28 — — US disclosed
US-20080188638-A1 Heterobifunctional poly(ethyleneglycol) containing acid-labile amino protecting groups and uses thereof INTEZYNE TECHNOLOGIES (US) 2008-08-07 — — US disclosed
CN-1016000-B SIZING AGENT CHIYODA KENKYUSHO K K (JP) 1992-03-25 — — CN disclosed
CN-87104680-A SIZING AGENT — 1988-12-14 — — CN disclosed
EP-0252289-A2 Transesterification catalysts and thermoset coatings THE GLIDDEN COMPANY (US) 1988-01-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound EPCAM, CDH1, DNMT3L TSHR 4764/4885ALDH1A1 2511/4885TAAR1 1318/4885
US-20080188638-A1 Heterobifunctional poly(ethyleneglycol) containing acid-labile amino protecting groups and uses thereof LNPEP, GNE, DNPEP TSHR 4327/4885ALDH1A1 2599/4885TAAR1 4028/4885
US-20240067672-A1 FLAVONE DERIVATIVE FOR TREATING TUMORS AND USE THEREOF TPD52L2, F12, H1-0 TSHR 4421/4885ALDH1A1 1467/4885TAAR1 4739/4885
US-20080207913-A1 Poly(ethylene glycol) containing chemically disparate endgroups GNE, EPRS1, ALG1 TSHR 3867/4885ALDH1A1 2008/4885TAAR1 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.