Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 13/20 | 0.38 |
| ▸ | ACHE | P22303 | 13/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208616 | 0.74 | TSHR (0.60) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL424728 | 0.72 | TSHR (0.73) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL4163120 | 0.72 | ACHE (0.44) | TSHRLMNAACHEALDH1A1MAPT | |
| SCHEMBL10621839 | 0.70 | TSHR (0.48) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL311787 | 0.69 | — | — | |
| SCHEMBL7785831 | 0.68 | HDAC1 (0.45) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL3625528 | 0.67 | NPC1 (0.52) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL338386 | 0.67 | BCHE (0.52) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL23253599 | 0.67 | TSHR (0.44) | TSHRLMNATYRBCHEACHE | |
| SCHEMBL8428815 | 0.67 | CA1 (0.52) | ACHEALDH1A1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866306-A | POLYALKYLPHENYLSILANE | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-02-02 | — | — | US | disclosed |