SCHEMBL208616

SCHEMBL208616

CC(C)(C)c1ccc([SiH2]c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
KIF11 P52732 2/20 0.42
ALDH1A1 P00352 4/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
MAPK1 P28482 1/20 0.39
HDAC1 Q13547 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
SLC22A3 O75751 1/20 0.39
BCHE P06276 3/20 0.39
ACHE P22303 3/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SRD5A2 P31213 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27887339 0.90 TSHR (0.50) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL424728 0.80 TSHR (0.73) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL10621839 0.78 TSHR (0.48) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL166690 0.75 TSHR (1.00) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL5495871 0.75 TSHR (1.00) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL23253599 0.74 TSHR (0.44) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL8430637 0.74 TSHR (0.44) TSHRLMNATYRKIF11ALDH1A1
Methylamine SCHEMBL28294591 0.74 TSHR (0.65) TSHRLMNATYRKIF11ALDH1A1
Hydrogen Sulfide SCHEMBL27843123 0.73 TSHR (0.94) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL3423876 0.71 KIF11 (0.70) TSHRLMNATYRKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283536-B1 CATALYSTS FOR CONTROL OF LONG CHAIN BRANCHING UNIVATION TECH LLC (US) 2024-07-17 EP disclosed
WO-2024127977-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND ACID DIFFUSION CONTROL AGENT 東京応化工業株式会社 2024-06-20 WO disclosed
WO-2024129637-A1 DECREASING TRIBOELECTRIC CHARGING OF, AND/OR REACTOR FOULING BY, POLYOLEFIN PARTICLES UNIVATION TECHNOLOGIES, LLC (US) 2024-06-20 WO disclosed
WO-2024122425-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND ACID DIFFUSION CONTROL AGENT 東京応化工業株式会社 2024-06-13 WO disclosed
EP-3189062-B1 PROCESS FOR PRODUCING CATALYST ACTIVATORS UNIVATION TECH LLC (US) 2024-05-01 EP disclosed
EP-3747913-B1 CONTINUITY COMPOSITIONS AND OLEFIN POLYMERISATION METHOD USING THE SAME UNIVATION TECH LLC (US) 2024-04-17 EP disclosed
US-11952480-B2 Enhanced processability of LLDPE by addition of ultra-high molecular weight density polyethylene EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-04-09 US disclosed
EP-3663323-B1 PRODUCING POLYOLEFIN PRODUCTS UNIVATION TECH LLC (US) 2024-03-20 EP disclosed
US-20240076427-A1 PRODUCING POLYOLEFIN PRODUCTS UNIVATION TECHNOLOGIES, LLC (US) 2024-03-07 US disclosed
EP-3105258-B1 METHOD OF PRODUCING POLYETHYLENE UNIVATION TECH LLC (US) 2024-03-06 EP disclosed
WO-2004022230-A1 PROCESS FOR PRODUCING FLUORINATED CATALYSTS UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
WO-2004022607-A1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
US-20040044153-A1 Gas phase polymerization process UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040044154-A1 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040043893-A1 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO disclosed
WO-2004003032-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2004-01-08 WO disclosed
US-20030171514-A1 Polymerization catalyst activator complexes and their use in a polymerization process DOW GLOBAL TECHNOLOGIES LLC 2003-09-11 US disclosed
WO-2003064435-A1 POLYMERIZATION CATALYST ACTIVATOR COMPLEXES AND THEIR USE IN A POLYMERIZATION PROCESS UNIVATION TECHNOLOGIES, LLC (US) 2003-08-07 WO disclosed
US-20030105251-A1 Methods for adjusting melt properties of metallocene catalyzed olefin copolymers UNIVATION TECHNOLOGIES, LLC 2003-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076427-A1 PRODUCING POLYOLEFIN PRODUCTS DNMT1, DNMT3B, DNMT3L TSHR 3570/4885LMNA 1882/4885TYR 3459/4885
US-20040043893-A1 Process for producing fluorinated catalysts FLI1, AFF1, INF2 TSHR 3467/4885LMNA 2788/4885TYR 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.