Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938027 | 0.87 | ALDH1A1 (0.39) | TSHRALDH1A1LDHA | |
| Bicarbonate SCHEMBL10449780 | 0.77 | ALDH1A1 (0.41) | TSHRALDH1A1HPGD | |
| SCHEMBL28375180 | 0.75 | ALDH1A1 (0.34) | ALDH1A1LDHA | |
| SCHEMBL28375178 | 0.75 | ALDH1A1 (0.34) | ALDH1A1LDHA | |
| SCHEMBL31375734 | 0.74 | — | — | |
| Propene SCHEMBL25168286 | 0.70 | — | — | |
| SCHEMBL27486033 | 0.70 | — | — | |
| Propene SCHEMBL27852734 | 0.70 | HSD17B10 (0.42) | TSHRALDH1A1 | |
| Bicarbonate SCHEMBL28800487 | 0.70 | LMNA (0.41) | TSHRALDH1A1 | |
| 2-Methoxyethanol SCHEMBL5954194 | 0.70 | TSHR (0.41) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0755384-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028391-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |