Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.35 |
| ▸ | RGS8 | P57771 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069598 | 0.91 | TP53 (0.33) | ARGRM5TP53MAPT | |
| SCHEMBL10069606 | 0.91 | ALDH1A1 (0.37) | ARALDH1A1MAPK1POLBCTSB | |
| SCHEMBL10069611 | 0.89 | L3MBTL1 (0.36) | ARALDH1A1GNRHRKDM4EGRM5 | |
| SCHEMBL10069631 | 0.88 | RGS4 (0.34) | RGS4RGS8ARALDH1A1KDM4E | |
| SCHEMBL10069619 | 0.88 | KDM5B (0.34) | ARGNRHRTP53MAPT | |
| SCHEMBL10069601 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPK1GNRHRKDM4EHPGD | |
| SCHEMBL10069626 | 0.83 | HPD (0.34) | ALDH1A1MAPK1POLBCTSB | |
| SCHEMBL10069596 | 0.83 | MAPT (0.36) | RGS4RGS8ALDH1A1MAPK1POLB | |
| SCHEMBL10069595 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPK1GRM5LMNA | |
| SCHEMBL10069590 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPK1POLBCTSSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |