SCHEMBL8430903

SCHEMBL8430903

O=C(O)Oc1ccc2oc3ccc(OC(=O)O)cc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
KDM4E B2RXH2 11/20 0.48
RXFP1 Q9HBX9 1/20 0.48
ALDH1A1 P00352 9/20 0.47
HPGD P15428 6/20 0.47
NPC1 O15118 5/20 0.47
RAB9A P51151 4/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
POLB P06746 2/20 0.45
KMT2A Q03164 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
FLT3 P36888 1/20 0.44
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240234 0.91 LMNA (0.66) LMNAKDM4ERXFP1ALDH1A1HPGD
SCHEMBL14541242 0.86 CA12 (0.58) LMNAKDM4ERXFP1ALDH1A1HPGD
SCHEMBL9413588 0.84 NPC1 (0.68) LMNAKDM4EALDH1A1HPGDNPC1
SCHEMBL11465493 0.83 KDM4E (0.50) KDM4ERXFP1ALDH1A1HPGDNPC1
SCHEMBL10785566 0.82 ALDH1A1 (0.66) LMNAKDM4ERXFP1ALDH1A1HPGD
SCHEMBL9809610 0.79 KDM4E (0.56) KDM4ERXFP1ALDH1A1HPGDNPC1
SCHEMBL20322895 0.79 LMNA (0.60) LMNAKDM4ERXFP1ALDH1A1HPGD
SCHEMBL11462931 0.79 KMT2A (0.60) LMNARXFP1ALDH1A1NPC1RAB9A
SCHEMBL14541247 0.78 NPC1 (0.54) LMNAKDM4ERXFP1ALDH1A1HPGD
SCHEMBL341673 0.76 LMNA (0.85) LMNAKDM4EALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761705-B1 Liquid one-component polyurethane storing lacquers DEGUSSA (DE) 1999-11-24 EP disclosed
EP-0761705-A1 Liquid one-component polyurethane storing lacquers HÜLS AKTIENGESELLSCHAFT (DE) 1997-03-12 EP disclosed
EP-0045997-B1 STOVING VARNISH HÜLS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP disclosed
EP-0001468-B1 POWDERED COATING PRODUCTS, PROCESS FOR THEIR PREPARATION AND THEIR USE CHEMISCHE WERKE HÜLS AG (DE) 1982-05-12 EP disclosed
EP-0045997-A1 Stoving varnish HÜLS AKTIENGESELLSCHAFT (DE) 1982-02-17 EP disclosed
EP-0001467-B1 STOVING LACQUERS HAVING AN EXTENDED POT LIFE ON THE BASIS OF POLYISOCYANATE MASKED WITH IMIDAZOLINES CHEMISCHE WERKE HÜLS AG (DE) 1981-10-21 EP disclosed
EP-0023023-A1 Pulverulent coating masses having an extended pot-life, and their preparation CHEMISCHE WERKE HÜLS AG (DE) 1981-01-28 EP disclosed
EP-0001468-A1 Powdered coating products, process for their preparation and their use CHEMISCHE WERKE HÜLS AG (DE) 1979-04-18 EP disclosed
EP-0001467-A1 Stoving lacquers having an extended pot life on the basis of polyisocyanate masked with imidazolines CHEMISCHE WERKE HÜLS AG (DE) 1979-04-18 EP disclosed