SCHEMBL9809610

SCHEMBL9809610

O=C(O)Oc1ccc2c(=O)c3ccc(OC(=O)O)cc3oc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.56
ALDH1A1 P00352 7/20 0.56
KMT2A Q03164 5/20 0.56
HPGD P15428 2/20 0.56
MEN1 O00255 2/20 0.56
TP53 P04637 1/20 0.56
CYP2C9 P11712 1/20 0.56
PTGER1 P34995 1/20 0.56
PTGER3 P43115 1/20 0.56
PTGER2 P43116 1/20 0.56
PTGDR Q13258 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MAPT P10636 5/20 0.55
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
MAOA P21397 2/20 0.53
GLA P06280 4/20 0.53
GAA P10253 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
PPARG P37231 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9809595 0.83 KMT2A (0.72) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL9413588 0.82 NPC1 (0.68) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL7328681 0.81 NPC1 (0.68) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL8430903 0.79 LMNA (0.53) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL20317223 0.79 KDM4E (0.62) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL8961859 0.79 ALDH1A1 (0.72) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL11499651 0.78 KDM4E (0.54) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL10785566 0.78 ALDH1A1 (0.66) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL27698750 0.77 KDM4E (0.54) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL27698748 0.77 KDM4E (0.56) KDM4EALDH1A1KMT2AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0198798-B1 LIGHT-SENSITIVE POLYCONDENSATES, PROCESS FOR THEIR PREPARATION, MATERIALS COATED THEREWITH AND THEIR USE CIBA-GEIGY AG (CH) 1991-05-29 EP disclosed
EP-0198798-A2 Light-sensitive polycondensates, process for their preparation, materials coated therewith and their use CIBA-GEIGY AG (CH) 1986-10-22 EP disclosed