Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431329 | 0.90 | ALDH1A1 (0.38) | FLT3MAOBCYP19A1MAPTMEN1 | |
| SCHEMBL8306599 | 0.84 | FLT3 (0.47) | FLT3MAOBCYP19A1MAPTMEN1 | |
| SCHEMBL8306598 | 0.77 | AKT1 (0.40) | FLT3MAPTPOLBOPRD1APP | |
| SCHEMBL8304396 | 0.76 | MAOB (0.59) | FLT3MAOBCYP19A1MAPTMEN1 | |
| SCHEMBL8309183 | 0.75 | MAOB (0.51) | FLT3MAOBCYP19A1MAPTMEN1 | |
| SCHEMBL8309111 | 0.74 | ABCB1 (0.57) | FLT3MAOBCYP19A1MAPTMEN1 | |
| SCHEMBL8429317 | 0.73 | HPGD (0.56) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8427197 | 0.73 | PTGS1 (0.36) | FLT3MAPTPOLBOPRD1ALDH1A1 | |
| SCHEMBL8308992 | 0.71 | MAOB (0.39) | FLT3MAOBMAPTMEN1KMT2A | |
| SCHEMBL8310185 | 0.70 | MAOB (0.41) | FLT3MAOBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |