Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161431 | 0.79 | MCL1 (0.72) | MCL1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1020499 | 0.79 | MCL1 (0.56) | MCL1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL8121527 | 0.78 | MCL1 (0.70) | MCL1PLK1ALDH1A1MAPTGAA | |
| SCHEMBL6182687 | 0.78 | PLK1 (0.61) | PLK1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL30826508 | 0.78 | MCL1 (0.55) | MCL1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11757507 | 0.77 | PLK1 (0.49) | PLK1HPGDALDH1A1NPC1MAPT | |
| SCHEMBL6841440 | 0.76 | SIRT1 (0.59) | MCL1PLK1HPGDMAPTGAA | |
| SCHEMBL22431606 | 0.76 | MCL1 (0.45) | MCL1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL3152318 | 0.75 | CA12 (0.62) | MCL1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL21951012 | 0.75 | ALDH1A1 (0.65) | MCL1HPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891995-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | AVENTIS PHARMACEUTICALS INC. | 1999-04-06 | — | — | US | disclosed |
| US-5684131-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | LEBL MICHAL (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0579785-B1 | SUBSTITUTED BENZHYDRYLAMINES AS HANDLES FOR SOLID PHASE PEPTIDE SYNTHESIS | LEBL MICHAL (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0579785-A4 | SUBSTITUTED BENZHYDRYLAMINES AS HANDLES FOR SOLID PHASE PEPTIDE SYNTHESIS | LEBL MICHAL (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0579785-A1 | SUBSTITUTED BENZHYDRYLAMINES AS HANDLES FOR SOLID PHASE PEPTIDE SYNTHESIS. | LEBL MICHAL (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018144-A1 | SUBSTITUTED BENZHYDRYLAMINES AS HANDLES FOR SOLID PHASE PEPTIDE SYNTHESIS | LEBL MICHAL (US) | 1992-10-29 | — | — | WO | disclosed |