Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182687 | 0.84 | PLK1 (0.61) | GAAMAPTL3MBTL1PLK1CYP1A2 | |
| SCHEMBL1758192 | 0.82 | CA12 (0.68) | SIRT1CA12CA1CA2CA7 | |
| SCHEMBL15459684 | 0.81 | PLK1 (0.47) | SIRT1GAAMAPTL3MBTL1PLK1 | |
| SCHEMBL7588971 | 0.80 | LMNA (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6839571 | 0.79 | ALDH1A1 (0.67) | SIRT1CA12CA1CA2CA7 | |
| SCHEMBL5476111 | 0.78 | MAPT (0.68) | SIRT1CA12CA1CA2CA7 | |
| SCHEMBL31472599 | 0.78 | HAO1 (0.58) | GAAMAPTPTGS2PLK1CYP1A2 | |
| SCHEMBL8431978 | 0.76 | MCL1 (0.51) | MCL1GAAMAPTPLK1CYP1A2 | |
| SCHEMBL7810350 | 0.76 | SRD5A2 (0.62) | KDM4EMAPTPLK1CYP1A2CYP3A4 | |
| SCHEMBL7802223 | 0.76 | CES2 (0.52) | PLK1CYP1A2CYP3A4CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759367-B2 | COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER | AGFA-GEVAERT (BE) | 2004-07-06 | — | — | US | disclosed |