Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 8/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | STK25 | O00506 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | MUSK | O15146 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL842371 | 0.99 | CDK2 (0.37) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| Hydrochloric Acid SCHEMBL842650 | 0.99 | CDK2 (0.37) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2253885 | 0.99 | CDK2 (0.37) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2251435 | 0.96 | CDK2 (0.38) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2252579 | 0.95 | UBE2M (0.37) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2251489 | 0.94 | UBE2M (0.36) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2251396 | 0.94 | UBE2M (0.36) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL4094280 | 0.94 | CDK2 (0.37) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2250983 | 0.93 | MCHR1 (0.38) | CDK2CDK8CDK1UBE2MDCUN1D1 | |
| SCHEMBL2250085 | 0.93 | UBE2M (0.38) | CDK2CDK8CDK1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790637-B1 | Derivatives of N-4-piperidyl urea and medicaments containing them as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2014-01-29 | — | — | EP | claimed |
| EP-2546234-A1 | Nitrogeneous heterocyclic derivative and medicine containing the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-01-16 | — | — | EP | claimed |
| US-8143404-B2 | N-heterocycle urea compounds such as 5-([(butyl{1-[(2-methyl-6-{4-[(methylsulfonyl)amino]phenoxy)-3-pyridinyl)methyl]-4-piperidinyl}amino)carbonyl]amino)-2,4-difluorobenzamide; chemokine receptor CCR5 antagonists for various inflammatory diseases, autoimmune diseases, infectious diseases | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-27 | — | — | US | claimed |
| US-20080057074-A1 | Nitrogenous Heterocylic Derivative and Medicine Containing the Same as an Active Ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-03-06 | — | — | US | claimed |
| EP-1790637-B1 | Derivatives of N-4-piperidyl urea and medicaments containing them as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2014-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057074-A1 | Nitrogenous Heterocylic Derivative and Medicine Containing the Same as an Active Ingredient | CXCR3, CCR5, CCR1 | CDK2 402/4885CDK8 647/4885CDK1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.