Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2018627 | 0.74 | CALM1 (0.41) | IDH1CALM1CYP3A4CYP2D6TSHR | |
| SCHEMBL9139369 | 0.73 | TP53 (0.41) | IDH1CALM1RAPGEF4CYP3A4CYP2D6 | |
| SCHEMBL7819859 | 0.69 | CALM1 (0.48) | L3MBTL1IDH1CALM1CYP1A2CYP2A6 | |
| SCHEMBL2091627 | 0.67 | CALM1 (0.57) | IDH1CALM1BCL2BCL2L1 | |
| SCHEMBL317298 | 0.67 | RAPGEF4 (0.33) | RAPGEF4 | |
| SCHEMBL7463268 | 0.66 | CALM1 (0.44) | L3MBTL1CALM1CYP2A6CYP3A4MAPT | |
| SCHEMBL17180545 | 0.66 | TAAR1 (0.38) | IDH1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9496827 | 0.64 | CALM1 (0.60) | IDH1CALM1CYP3A4TSHRMAPT | |
| SCHEMBL5027093 | 0.64 | CALM1 (0.60) | IDH1CALM1CYP2D6BCL2BCL2L1 | |
| SCHEMBL2852601 | 0.63 | CALM1 (0.41) | L3MBTL1IDH1CALM1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952152-A | POLYMERIZABLE MIXTURE COMPRISING AT LEAST ONE ETHYLENICALLY UNSATURATED COMPOUND AND AN ANIONIC BORON COMPOUND ACTIVATOR | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |