Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | RXRB | P28702 | 4/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827276 | 0.94 | HPGD (0.56) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL30268201 | 0.89 | NPSR1 (0.66) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL8079678 | 0.85 | NPSR1 (0.60) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL28125163 | 0.83 | XDH (0.63) | SRD5A2NPSR1HPGDMCOLN3RXRA | |
| SCHEMBL8433883 | 0.82 | SRD5A2 (0.47) | SRD5A2NPSR1HPGDMCOLN3RXRA | |
| SCHEMBL8437651 | 0.81 | SRD5A2 (0.46) | SRD5A2NPSR1HPGDMCOLN3RXRA | |
| SCHEMBL8435617 | 0.81 | SRD5A2 (0.46) | SRD5A2NPSR1HPGDMCOLN3RXRA | |
| SCHEMBL458409 | 0.79 | NPSR1 (0.59) | NPSR1HPGDMCOLN3KDM4EALDH1A1 | |
| SCHEMBL8434370 | 0.79 | SRD5A2 (0.54) | SRD5A2RXRARXRBRXRGBCL2L1 | |
| SCHEMBL8691793 | 0.79 | NPSR1 (0.58) | SRD5A2NPSR1HPGDMCOLN3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |