Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 5/20 | 0.41 |
| ▸ | RXRB | P28702 | 5/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435617 | 0.87 | SRD5A2 (0.46) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL8437445 | 0.86 | SRD5A2 (0.47) | SRD5A2LMNA | |
| SCHEMBL8437651 | 0.84 | SRD5A2 (0.46) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL8433248 | 0.82 | SRD5A2 (0.59) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL1827276 | 0.80 | HPGD (0.56) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL8078533 | 0.79 | SRD5A2 (0.51) | SRD5A2LMNA | |
| SCHEMBL8070686 | 0.74 | LMNA (0.49) | SRD5A2LMNA | |
| SCHEMBL28125163 | 0.74 | XDH (0.63) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL30268201 | 0.72 | NPSR1 (0.66) | SRD5A2NPSR1HPGDMCOLN3KDM4E | |
| SCHEMBL1142324 | 0.71 | NPSR1 (0.54) | NPSR1HPGDMCOLN3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |