Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433248 | 0.79 | SRD5A2 (0.59) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL13185575 | 0.79 | TP53 (0.46) | SRD5A2RXRARXRBRXRGPTGS2 | |
| SCHEMBL8079980 | 0.79 | TYR (0.47) | GRIA4PTGS2 | |
| SCHEMBL14127824 | 0.78 | KCNA5 (0.50) | PTGS2 | |
| SCHEMBL2627825 | 0.76 | RXRA (0.68) | GRIA4RXRARXRBRXRGCA12 | |
| SCHEMBL9330598 | 0.74 | RXRA (0.56) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL4488292 | 0.74 | PTGS2 (0.61) | SRD5A2PTGS2 | |
| SCHEMBL6688306 | 0.74 | PTGS2 (0.61) | SRD5A2PTGS2 | |
| SCHEMBL8833485 | 0.74 | TSHR (0.55) | SRD5A2RXRARXRBRXRGPTGS2 | |
| SCHEMBL31192242 | 0.73 | TSHR (0.60) | SRD5A2RXRARXRBRXRGCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |