SCHEMBL8433259

SCHEMBL8433259

CC(=CCNc1nc2ncncc2[nH]1)CO

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
RECQL P46063 1/20 0.46
METAP2 P50579 1/20 0.34
METAP1 P53582 1/20 0.34
CYP1A2 P05177 1/20 0.33
CDK2 P24941 1/20 0.33
ENPP1 P22413 1/20 0.32
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3739252 1.00 TSHR (0.46) TSHRRECQLMETAP2METAP1CYP1A2
SCHEMBL4665814 0.88 CDK2 (0.43) TSHRRECQLMETAP2METAP1CYP1A2
SCHEMBL16969365 0.80 METAP2 (0.36) METAP2METAP1ENPP1NPY5R
SCHEMBL432903 0.78 ALDH1A1 (0.40) METAP2METAP1ENPP1NPY5R
SCHEMBL5934354 0.74 RIPK1 (0.40) TSHRMETAP2METAP1ENPP1NPY5R
SCHEMBL5467573 0.72 METAP2 (0.34) METAP2METAP1CYP1A2ENPP1NPY5R
SCHEMBL5072700 0.71 METAP2 (0.44) METAP2METAP1CYP1A2ENPP1NPY5R
SCHEMBL3421963 0.71 METAP2 (0.44) METAP2METAP1ENPP1NPY5R
SCHEMBL9980473 0.70 XDH (0.50) TSHRMETAP2METAP1NPY5R
SCHEMBL7145736 0.69 NPY5R (0.38) METAP2METAP1ENPP1NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856191-A CULTURING OF EMBROYOGENIC TISSUE IS CONTINUED ON CULTURE MAINTENANCE MEDIUM, EMBROY DEVELOPMENT MEDIUM AND GERMINATION MEDIUM, GERMINATED EMBROYS ARE FURTHER CONVERTED TO ACCLIMATIZATION PLANTS FOR FIELD PLANTING WESTVACO CORPORATION (US) 1999-01-05 US disclosed
US-5677185-A Method for regeneration of coniferous plants by somatic embryogenesis in culture media containing abscisic acid WESTVACO CORPORATION (US) 1997-10-14 US disclosed
EP-0584068-A4 1994-04-06 EP disclosed
EP-0584068-A1 METHOD AND COMPOSITION FOR AMELIORATING THE ADVERSE EFFECTS OF AGING SENETEK, PLC (US) 1994-03-02 EP disclosed
WO-1992020341-A1 METHOD AND COMPOSITION FOR AMELIORATING THE ADVERSE EFFECTS OF AGING SENETEK, PLC (US) 1992-11-26 WO disclosed