Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701403 | 0.94 | CYP1A2 (0.60) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29025449 | 0.89 | CYP1A2 (0.56) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8070439 | 0.82 | HTR1A (0.62) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL720666 | 0.80 | POLB (0.66) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30874782 | 0.80 | SMN1; SMN2 (0.55) | CYP1A2CYP2D6CYP2C9CYP2C19POLB | |
| SCHEMBL28069319 | 0.79 | CYP1A2 (0.64) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28583505 | 0.79 | TDP1 (0.64) | DRD2DRD3MAPTMEN1KMT2A | |
| SCHEMBL3378195 | 0.78 | HDAC3 (0.65) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8374787 | 0.76 | MAPT (0.62) | HTR1AHTR7CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30530187 | 0.76 | LMNA (0.50) | CYP1A2CYP2D6CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1995026722-A1 | METHOD FOR INHIBITING MAST CELL AND BASOPHIL ACTIVATION | CELL THERAPEUTICS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |