Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432748 | 0.86 | MAOB (0.56) | MAOBMAOANR4A2APPPPARA | |
| SCHEMBL8431672 | 0.86 | MAOB (0.58) | MAOBMAOAFFAR1 | |
| SCHEMBL8434262 | 0.79 | MAOB (0.58) | NPC1RAB9AMAOBMAOAFFAR1 | |
| SCHEMBL8431815 | 0.79 | MAOB (0.67) | MAOBMAOANR4A2PPARA | |
| SCHEMBL8433722 | 0.78 | SCN9A (0.67) | MAOB | |
| SCHEMBL23440948 | 0.77 | MAOB (0.65) | NPC1RAB9AMAOBMAOAMEN1 | |
| SCHEMBL11511023 | 0.76 | MAOB (0.56) | NPC1RAB9AMAOBMAOANR4A2 | |
| SCHEMBL21991256 | 0.76 | MAOB (0.63) | NPC1RAB9AMAOBMAOANR4A2 | |
| SCHEMBL8433404 | 0.75 | NPC1 (0.64) | NPC1RAB9AMAOBMAOANR4A2 | |
| SCHEMBL11511079 | 0.75 | ALDH1A1 (0.56) | NPC1RAB9AMAOBMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | claimed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |