Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431672 | 0.86 | MAOB (0.58) | MAOBFFAR1MAOAADAMTS4MMP13 | |
| SCHEMBL8431815 | 0.86 | MAOB (0.67) | MAOBPARP10MAOASCN9A | |
| SCHEMBL8432748 | 0.79 | MAOB (0.56) | MAOBFFAR1PARP10MAOAADAMTS4 | |
| SCHEMBL8433399 | 0.79 | NPC1 (0.57) | MAOBFFAR1MAOAMMP2MMP9 | |
| SCHEMBL8434265 | 0.78 | PARP15 (0.58) | MAOBFFAR1FFAR4PARP15PARP10 | |
| SCHEMBL6029226 | 0.77 | FFAR1 (0.67) | MAOBFFAR1FFAR4PARP15PARP10 | |
| SCHEMBL27881288 | 0.76 | MAOB (0.65) | MAOBFFAR1FFAR4PARP15PARP10 | |
| SCHEMBL8433722 | 0.76 | SCN9A (0.67) | MAOBPARP15PARP10PARP14SCN9A | |
| SCHEMBL3967573 | 0.75 | PARP15 (0.60) | MAOBFFAR1FFAR4PARP15PARP10 | |
| SCHEMBL8434311 | 0.74 | MAOB (0.58) | MAOBPARP10MAOASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | claimed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |