Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431323 | 0.98 | HPGD (0.33) | HPGDMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28798980 | 0.90 | HPGD (0.30) | HPGD | |
| SCHEMBL3502895 | 0.80 | MEN1 (0.33) | HPGDMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28790563 | 0.79 | EPHX1 (0.35) | HPGDSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL2373613 | 0.78 | HPGD (0.41) | HPGDMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16349436 | 0.78 | ALDH1A1 (0.38) | HPGDMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL18166970 | 0.78 | CHRM2 (0.38) | HPGDALDH1A1 | |
| SCHEMBL19638334 | 0.78 | — | — | |
| SCHEMBL5875413 | 0.77 | MEN1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL980149 | 0.77 | MLYCD (0.32) | HPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1654 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381941-A | SUMO-associated modified small molecule antagonists of CRMP2 and uses thereof | 代表亚利桑那大学的亚利桑那校董会 | 2019-10-25 | — | — | CN | claimed |
| CN-107001382-B | Spiral shell-thiazolone | 豪夫迈·罗氏有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110248932-A | Pyrimidine tricycloalkenone derivatives for ROR γ inhibition and other uses | 里亚塔医药公司 | 2019-09-17 | — | — | CN | claimed |
| CN-106660955-B | Cyclohexene derivative, preparation method and the pharmaceutical composition for being used to prevent or treat metabolic disease comprising it as active constituent | 现代药品株式会社 | 2019-08-23 | — | — | CN | claimed |
| CN-106841544-B | A kind of purple sweet potato pears compound fruit vinegar sample measurement system and its working method based on Plasma-MIG control | 徐州工程学院 | 2019-08-06 | — | — | CN | claimed |
| CN-110088100-A | Pyrimidone derivatives as CDC7 inhibitor | 癌症研究科技有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | claimed |
| CN-110036006-A | The preparation and use of pyrimidone derivatives | 癌症研究科技有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-105764514-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2019-07-12 | — | — | CN | claimed |
| CN-109890814-A | Include benzo [D] [1,3] oxygen thia cyclopentene, benzo [D] [1,3] method/purposes of the compound and its agonist as g protein coupled receptor 119 of oxygen thia cyclopentene 3- oxide or benzo [D] [1,3] oxygen thia cyclopentene 3,3- dioxide | 普拉马纳制药公司 | 2019-06-14 | — | — | CN | claimed |
| CN-101896481-A | Pyrimidyl indoline compound | DAIICHI SANKYO CO LTD | 2010-11-24 | — | — | CN | claimed |
| CN-101883762-A | Benzothiazoles as modulators of growth hormone releasing hormone receptors | ASTRAZENECA AB | 2010-11-10 | — | — | CN | claimed |
| CN-101616901-A | Inhibitors of phosphodiesterase type IV | RANBAXY LAB LTD | 2009-12-30 | — | — | CN | claimed |
| CN-101528739-A | N- (2 -hydroxyethyl) -n-methyl- 4- (quinolin- 8-yl (1- (thiazol-4- ylmethyl) piperidin- 4 -ylidene) methyl) benzamide, the process of making it as well as its use for the treatment of pain, anxiety an | ASTRAZENECA AB (SE) | 2009-09-09 | — | — | CN | claimed |
| CN-101454292-A | Bicyclic benzimidazole compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB (SE) | 2009-06-10 | — | — | CN | claimed |
| CN-101203504-A | Antimicrobial agents | RANBAXY LAB LTD (IN) | 2008-06-18 | — | — | CN | claimed |
| CN-101184761-A | Spiro-indolone compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2008-05-21 | — | — | CN | claimed |
| CN-101103016-A | Inhibitors of 11-beta hydroxyl steroid dehydrogenase type I and methods of using the same | INCYTE CORP (US) | 2008-01-09 | — | — | CN | claimed |
| CN-101080226-A | Amido compounds and their use as pharmaceuticals | INCYTE CORP (US) | 2007-11-28 | — | — | CN | claimed |
| CN-101068825-A | Having a2A2-propynyl adenosine analogs with modified 5' -ribose groups for agonist activity | UNIV VIRGINIA (US) | 2007-11-07 | — | — | CN | claimed |