SCHEMBL980149

SCHEMBL980149

O=C(ON1CCCCC1)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721518 0.98 MLYCD (0.33) MLYCD
SCHEMBL15355468 0.93
SCHEMBL938120 0.79
SCHEMBL27480810 0.78
SCHEMBL2728754 0.78 CA2 (0.34)
SCHEMBL14812645 0.78 SMN1; SMN2 (0.40) MLYCDALDH1A1MEN1HPGDTSHR
SCHEMBL8433485 0.77 HPGD (0.36) ALDH1A1MEN1HPGDKMT2A
SCHEMBL27758892 0.77 HPGD (0.36) ALDH1A1MEN1HPGDKMT2A
SCHEMBL5875413 0.77 MEN1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL4307041 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350150-A 4-Butoxyphenyl propenone and preparation method and application thereof 北京茗泽中和药物研究有限公司 2025-01-24 CN claimed
CN-115974664-A Synthesis method of 5-chloro-1-indanone 合肥工业大学 2023-04-18 CN claimed
EP-1926721-B1 THIOPHENE AND THIAZOLE SUBSTITUTED TRIFLUOROETHANONE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS MSD ITALIA SRL (IT) 2016-05-04 EP claimed
CN-1552328-A Use of phenoxthine compounds in preparing medicnies for inhibiting cancers and promoting radio-sensitive medicines 中国人民解放军军事医学科学院放射医 2004-12-08 CN claimed
EP-0562815-A1 Aromatic hydrocarbons separation from aromatic/non-aromatic mixtures EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-09-29 EP claimed
CN-107949384-B Muscarinic agonists 奈克斯拉制药英国有限公司 2025-02-28 CN disclosed
CN-119350150-A 4-Butoxyphenyl propenone and preparation method and application thereof 北京茗泽中和药物研究有限公司 2025-01-24 CN disclosed
CN-118164961-A 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) 迈奥卡迪亚公司 2024-06-11 CN disclosed
CN-111393414-B 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) 迈奥卡迪亚公司 2024-05-07 CN disclosed
CN-117396471-A Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same 株式会社次代生物科学 2024-01-12 CN disclosed
WO-2023242335-A2 CATALYTIC SYSTEM CONTAINING IONIC LIQUIDS AND A PROCESS FOR PRODUCING HYDROGEN FROM PLASTIC MATERIALS USING SAID CATALYTIC SYSTEM FUNDACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA DE ENERGÍAS ALTERNATIVAS CIC ENERGIGUNE FUNDAZIOA (ES) 2023-12-21 WO disclosed
CN-112204007-B Process for preparing 2- (1- (tert-butoxycarbonyl) piperidin-4-yl) benzoic acid 施万生物制药研发IP有限责任公司 2023-06-20 CN disclosed
WO-2000076970-A2 SERINE PROTEASE INHIBITORS ELI LILLY AND COMPANY (US) 2000-12-21 WO disclosed
WO-2000077027-A2 SERINE PROTEASE INHIBITORS TULARIK LIMITED (GB) 2000-12-21 WO disclosed
EP-1042313-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST LIKE ACTIVITY Allergan Sales, Inc. (US) 2000-10-11 EP disclosed
US-6057336-A ANTIINFLAMMATORY AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-02 US disclosed
US-5958954-A 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES ALLERGAN SALES, INC. (US) 1999-09-28 US disclosed
WO-1999033821-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST-LIKE ACTIVITY ALLERGAN SALES, INC. (US) 1999-07-08 WO disclosed
CN-1183770-A Piperazine derivatives, medicaments containing these compounds, their use and processes for their preparation THOMAE GMBH DR K (DE) 1998-06-03 CN disclosed
US-5532411-A Production of carboxylic acid halides and carboxylate salts SOLVAY FLUOR UND DERIVATE GMBH (DE) 1996-07-02 US disclosed